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1

Novel Biomarkers for Change in Renal Function in People With Dysglycemia

Gerstein, Hertzel C., Paré, Guillaume, McQueen, Matthew J., Lee, Shun Fu, Bangdiwala, Shrikant I., Kannt, Aimo, Hess, Sibylle

Journal:

Year:

2019

Language:

english

File:

PDF, 908 KB

english, 2019

2

Fehlbildungen des weiblichen Genitales; Female genital malformations;

Rall, K. K., Schöller, D., Lehmann-Kannt, S.

Journal:

Monatsschrift Kinderheilkunde

Year:

2017

Language:

german

File:

PDF, 1.40 MB

german, 2017

3

Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates

Elvert, Ralf, Herling, Andreas W., Bossart, Martin, Weiss, Tilo, Zhang, Baohong, Wenski, Pierre, Wandschneider, Jörn, Kleutsch, Sabrina, Butty, Uwe, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers

Journal:

Diabetes, Obesity and Metabolism

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

4

Incretin combination therapy for the treatment of non-alcoholic steatohepatitis

Kannt, Aimo, Nygaard Madsen, Andreas, Kammermeier, Claire, Elvert, Ralf, KlÃ¶ckener, Tim, Bossart, Martin, Haack, Torsten, Evers, Andreas, Lorenz, Katrin, Hennerici, Wolfgang, Rocher, Corinne, BÃ¶cske

Journal:

Diabetes, Obesity and Metabolism

Year:

2020

Language:

english

File:

PDF, 1.38 MB

english, 2020

5

Structural investigations of the CuA centre of nitrous oxide reductase from Pseudomonas stutzeri by site-directed mutagenesis and X-ray absorption spectroscopy

John M. Charnock, Andreas Dreusch, Heinz Körner, Frank Neese, Jane Nelson, Aimo Kannt, Hartmut Michel, C. David Garner, Peter M. H. Kroneck, Walter G. Zumft

Journal:

Year:

2000

Language:

english

File:

PDF, 1.58 MB

english, 2000

6

Probing the access of protons to the K pathway in the Paracoccus denitrificans cytochrome c oxidase

Oliver-M. H. Richter, Katharina L. Dürr, Aimo Kannt, Bernd Ludwig, Francesca M. Scandurra, Alessandro Giuffrè, Paolo Sarti, Petra Hellwig

Journal:

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

7

The Role of Electrostatic Interactions for CytochromecOxidase Function

Aimo Kannt, C. Roy D. Lancaster, Hartmut Michel

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1998

Language:

english

File:

PDF, 1.34 MB

english, 1998

8

Selective inhibitors of cardiac ADPR cyclase as novel anti-arrhythmic compounds

Aimo Kannt, Kerstin Sicka, Katja Kroll, Dieter Kadereit, Heinz Gögelein

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2012

Language:

english

File:

PDF, 462 KB

english, 2012

9

The role of acidic residues of plastocyanin in its interaction with cytochrome ƒ

Aimo Kannt, Simon Young, Derek S. Bendall

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1996

Language:

english

File:

PDF, 942 KB

english, 1996

10

The symbiotically essential cbb3-type oxidase of Bradyrhizobium japonicum is a proton pump

Engin Arslan, Aimo Kannt, Linda Thöny-Meyer, Hauke Hennecke

Journal:

Year:

2000

Language:

english

File:

PDF, 120 KB

english, 2000

11

Zn2+ binding to the cytoplasmic side of Paracoccus denitrificans cytochrome c oxidase selectively uncouples electron transfer and proton translocation

Aimo Kannt, Thomas Ostermann, Hannelore Müller, Maarten Ruitenberg

Journal:

Year:

2001

Language:

english

File:

PDF, 116 KB

english, 2001

12

Electrical current generation and proton pumping catalyzed by the ba3-type cytochrome c oxidase from Thermus thermophilus

Aimo Kannt, Tewfik Soulimane, Gerhard Buse, Anja Becker, Ernst Bamberg, Hartmut Michel

Journal:

Year:

1998

Language:

english

File:

PDF, 252 KB

english, 1998

13

CYTOCHROME C OXIDASE: Structure and Spectroscopy

Michel, H., Behr, J., Harrenga, A., Kannt, A.

Journal:

Annual Review of Biophysics and Biomolecular Structure

Year:

1998

Language:

english

File:

PDF, 431 KB

english, 1998

14

The Coupling of Electron Transfer and Proton Translocation: Electrostatic Calculations on Paracoccus denitrificans Cytochrome c Oxidase

Kannt, Aimo, Lancaster, C. Roy D., Michel, Hartmut

Journal:

Biophysical Journal

Year:

1998

Language:

english

File:

PDF, 1.12 MB

english, 1998

15

Novel β-Amino Acid Derivatives as Inhibitors of Cathepsin A

Ruf, Sven, Buning, Christian, Schreuder, Herman, Horstick, Georg, Linz, Wolfgang, Olpp, Thomas, Pernerstorfer, Josef, Hiss, Katrin, Kroll, Katja, Kannt, Aimo, Kohlmann, Markus, Linz, Dominik, Hübschle

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.82 MB

english, 2012

16

Expression patterning reveals retinal inflammation as a minor factor in experimental retinopathy of ZDF rats

Wohlfart, Paulus, Lin, Jihong, Dietrich, Nadine, Kannt, Aimo, Elvert, Ralf, Herling, Andreas W., Hammes, Hans-Peter

Journal:

Acta Diabetologica

Year:

2014

Language:

english

File:

PDF, 428 KB

english, 2014

17

Tyrosine 167: The Origin of the Radical Species Observed in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide in Paracoccus denitrificans †

Budiman, Kerstin, Kannt, Aimo, Lyubenova, Sevdalina, Richter, Oliver-Matthias H., Ludwig, Bernd, Michel, Hartmut, MacMillan, Fraser

Journal:

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

18

Tracing the D-Pathway in Reconstituted Site-Directed Mutants of Cytochrome c Oxidase from Paracoccus denitrificans †

Pfitzner, Ute, Hoffmeier, Klaus, Harrenga, Axel, Kannt, Aimo, Michel, Hartmut, Bamberg, Ernst, Richter, Oliver-M. H., Ludwig, Bernd

Journal:

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

19

Direct Evidence for a Tyrosine Radical in the Reaction of Cytochrome c Oxidase with Hydrogen Peroxide †

MacMillan, Fraser, Kannt, Aimo, Behr, Julia, Prisner, Thomas, Michel, Hartmut

Journal:

Year:

1999

Language:

english

File:

PDF, 64 KB

english, 1999

20

Electrochemistry suggests proton access from the exit site to the binuclear center in Paracoccus denitrificans cytochrome c oxidase pathway variants

Meyer, Thomas, Melin, Frédéric, Richter, Oliver-M.H., Ludwig, Bernd, Kannt, Aimo, Müller, Hanne, Michel, Hartmut, Hellwig, Petra

Journal:

Year:

2015

Language:

english

File:

PDF, 535 KB

english, 2015

21

GPR17 gene disruption does not alter food intake or glucose homeostasis in mice

Mastaitis, Jason, Min, Soo, Elvert, Ralf, Kannt, Aimo, Xin, Yurong, Ochoa, Francisca, Gale, Nicholas W., Valenzuela, David M., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 858 KB

english, 2015

22

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

Kannt, Aimo, Pfenninger, Anja, Teichert, Lenore, Tönjes, Anke, Dietrich, Arne, Schön, Michael R., Klöting, Nora, Blüher, Matthias

Journal:

Year:

2015

Language:

english

File:

PDF, 529 KB

english, 2015

23

Single-electron reduction of the oxidized state is coupled to proton uptake via the K pathway in Paracoccus denitrificans cytochrome c oxidase

Ruitenberg, M., Kannt, A., Bamberg, E., Ludwig, B., Michel, H., Fendler, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

24

Pharmacological Characterization of SAR407899, a Novel Rho-Kinase Inhibitor

Lohn, M., Plettenburg, O., Ivashchenko, Y., Kannt, A., Hofmeister, A., Kadereit, D., Schaefer, M., Linz, W., Kohlmann, M., Herbert, J.-M., Janiak, P., O'Connor, S. E., Ruetten, H.

Journal:

Year:

2009

Language:

english

File:

PDF, 7.49 MB

english, 2009

25

Length and weight of very low birth weight infants in Germany at 2 years of age: does it matter at what age they start complementary food?

Spiegler, J, Eisemann, N, Ehlers, S, Orlikowsky, T, Kannt, O, Herting, E, Göpel, W

Journal:

European Journal of Clinical Nutrition

Year:

2015

Language:

english

File:

PDF, 602 KB

english, 2015

26

Mutation of Arg-54 Strongly Influences Heme Composition and Rate and Directionality of Electron Transfer in Paracoccus denitrificans Cytochrome c Oxidase

Kannt, A., Pfitzner, U., Ruitenberg, M., Hellwig, P., Ludwig, B., Mantele, W., Fendler, K., Michel, H.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 705 KB

english, 1999

27

Management of nicotinamideN-methyltransferase overexpression: inhibit the enzyme or reduce nicotinamide intake? Reply to Zhou S, Li D, Zhou Y [letter]

Kannt, Aimo, Pfenninger, Anja, Tönjes, Anke, Blüher, Matthias

Journal:

Year:

2015

Language:

english

File:

PDF, 222 KB

english, 2015

28

Characterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling

Winkel, Angelika F., Engel, Christian K., Margerie, Daniel, Kannt, Aimo, Szillat, Hauke, Glombik, Heiner, Kallus, Christopher, Ruf, Sven, G&uumlssregen, Stefan, Riedel, Jens, Herling, Andreas W., von

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 4.51 MB

english, 2015

29

Reduction of cytochrome c oxidase by a second electron leads to proton translocation

Ruitenberg, Maarten, Kannt, Aimo, Bamberg, Ernst, Fendler, Klaus, Michel, Hartmut

Journal:

Year:

2002

Language:

english

File:

PDF, 619 KB

english, 2002

30

Managing risks in drug discovery: reproducibility of published findings

Kannt, Aimo, Wieland, Thomas

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2016

Language:

english

File:

PDF, 402 KB

english, 2016

31

Kindesmisshandlung aus pädiatrischer Sicht

Meyer, S., Poryo, M., Clasen, O., Schlote, J., Schmidt, P., Schöndorf, D., Lehmann-Kannt, S., Gortner, L.

Journal:

Year:

2016

Language:

german

File:

PDF, 251 KB

german, 2016

32

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

Qi, Weier, Keenan, Hillary A, Li, Qian, Ishikado, Atsushi, Kannt, Aimo, Sadowski, Thorsten, Yorek, Mark A, Wu, I-Hsien, Lockhart, Samuel, Coppey, Lawrence J, Pfenninger, Anja, Liew, Chong Wee, Qiang,

Journal:

Nature Medicine

Year:

2017

Language:

english

File:

PDF, 3.22 MB

english, 2017

33

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

Kannt, Aimo, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Suresh, Juluri, Bhamidipati, Ravi Kanth, Swaminathan, Srinivasan, Hallur, Mahanandeesha Siddappa, Kristam, Rajendra, Elvert, Ralf,

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.39 MB

english, 2018

34

Wirkstofffindung in kardiovaskulären und metabolischen Erkrankungen

Journal:

Year:

2017

Language:

german

File:

PDF, 295 KB

german, 2017

35

Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys

Elvert, Ralf, Bossart, Martin, Herling, Andreas W, Weiss, Tilo, Zhang, Baohong, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers, Andreas, Dudda, Angela, Keil, Stefanie, Lorenz, Martin, Lorenz, Kat

Journal:

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

36

Genetic Nicotinamide N-Methyltransferase ( Nnmt ) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance

Brachs, Sebastian, Polack, James, Brachs, Maria, Jahn-Hofmann, Kerstin, Elvert, Ralf, Pfenninger, Anja, Bärenz, Felix, Margerie, Daniel, Mai, Knut, Spranger, Joachim, Kannt, Aimo

Journal:

Year:

2018

Language:

english

File:

PDF, 2.09 MB

english, 2018

37

Cover Image, Volume 20, Issue 8

Elvert, Ralf, Herling, Andreas W., Bossart, Martin, Weiss, Tilo, Zhang, Baohong, Wenski, Pierre, Wandschneider, Jörn, Kleutsch, Sabrina, Butty, Uwe, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers

Journal:

Diabetes, Obesity and Metabolism

Year:

2018

File:

PDF, 238 KB

2018

38

High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT)

Policarpo, Rocco L., Decultot, Ludovic, May, Elizabeth, Kuzmic, Petr, Carlson, Samuel, Huang, Danny, Chu, Vincent, Wright, Brandon A., Dhakshinamoorthy, Saravanakumar, Kannt, Aimo, Rani, Shilpa, Ditta

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 20.89 MB

english, 2019

39

A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice

Wang, Xiaobo, Sommerfeld, Mark R., Jahn‐Hofmann, Kerstin, Cai, Bishuang, Filliol, Aveline, Remotti, Helen E., Schwabe, Robert F., Kannt, Aimo, Tabas, Ira

Journal:

Hepatology Communications

Year:

2019

Language:

english

File:

PDF, 2.13 MB

english, 2019

40

A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice

Wang, Xiaobo, Sommerfeld, Mark R., Jahn‐Hofmann, Kerstin, Cai, Bishuang, Filliol, Aveline, Remotti, Helen E., Schwabe, Robert F., Kannt, Aimo, Tabas, Ira

Journal:

Hepatology Communications

Year:

2019

File:

PDF, 2.13 MB

2019

41

Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease

Lin, Jihong, Hu, Jiong, Schlotterer, Andrea, Wang, Jing, Kolibabka, Matthias, Awwad, Khader, Dietrich, Nadine, Breitschopf, Kristin, Wohlfart, Paulus, Kannt, Aimo, Lorenz, Katrin, Feng, Yuxi, Popp, RÃ

Journal:

Year:

2020

File:

PDF, 2.38 MB

2020

42

AMPKÎ²1 and AMPKÎ²2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification

Ziegler, Nicole, Bader, Erik, Epanchintsev, Alexey, Margerie, Daniel, Kannt, Aimo, Schmoll, Dieter

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 3.63 MB

2020

43

Short-term variability of the human serum metabolome depending on nutritional and metabolic health status

Agueusop, Inoncent, Musholt, Petra B., Klaus, Beate, Hightower, Kendra, Kannt, Aimo

Journal:

Scientific Reports

Year:

2020

File:

PDF, 5.06 MB

2020

44

The novel phosphate and bile acid sequestrant polymer SAR442357 delays disease progression in a rat model of diabetic nephropathy

CastaÃ±eda, Tamara R., MÃ©ndez, MarÃa, Davison, Ian, Elvert, Ralf, Schwahn, Uwe, Boldina, Galina, Rocher, Corinne, Scherer, Petra, Singh, Kuldeep, Bangari, Dinesh, Falkenhan, Mechthilde, Kannt, Aimo,

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2020

File:

PDF, 18.48 MB

2020

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